Annatto-E® Synergy is a unique tocopherols-free, tocotrienols-only product, containing 125 mg tocotrienols along with 1 g black cumin seed oil (Nigella sativa) per two softgel serving. Vitamin E is not a single nutrient, but rather a complex made up of 8 distinct compounds: 4 tocopherols and 4 tocotrienols. These components have slightly different chemical structures, and these differences impart unique properties that influence their biochemical functions and their effects in the body. Most conventional supplements are typically rich in tocopherols—alpha- tocopherol, in particular—but the tocotrienol fractions have unique effects across a variety of tissues that make them desirable to supplement on their own, without tocopherols.

††An IPSOS 2023 survey among US functional medicine practitioners, in an average month, Designs for Health is their personally most trusted practitioner supplement brand, meaning a brand that is sold by healthcare practitioners in their office.

††An Ipsos 2023 study among a random sample of 160 functional medicine practitioners including Doctor's of Osteopathic Medicine, Pharmacists, Acupuncturists, Athletic Trainers, Personal Trainers, Fitness Trainer/Coaches, Chiropractors, Integrative Medicine Specialists, Naturopathic Doctor, Homeopaths, Medical Doctors, Physical Therapists, Nurse Practitioner/Physician Assistants, Registered Nurses, Nutritionists, Massage Therapists, Occupational Therapists and Dieticians that are aware of Designs for Health and recommend supplements to their patients.